A Clinicians’ Overview

Platelet Rich Plasma, The Angel System
The Angel Whole Blood Separation System

Platelet Rich Plasma, as a therapeutic technique, has a 20 year plus history. As PRP treatments have evolved, so has the technology behind the enrichment of plasma. At Biotherapy Services, we follow developments in the area very closely and for us, the Angel System from Cytomedix is currently best-of-breed. It’s what we use and what we recommend.

Biotherapy Services, composed of clinicians, technicians and healthcare managers, was created to bring the most effective platelet-enriching technology to medical practices in the UK and Eire.

It establishes a new level or consistency in whole blood separation; delivering high and specifiable platelet yields with reproducible results. With one-button automation, it is fast and simple to operate, and produces PRP in 17 minutes from insertion of the blood sample. The automated, closed system process is ideal for use in an outpatient environment, at the bedside, or in the operating theatre.

Talking technology, the Angel System uses sequential centrifuging to perform initial separation into red and plasma/platelet/white fractions, followed by a fine-tune spin which delivers the required precise platelet:plasma ratio. This is achieved with optical-sensor technology and automated valve switching. It accurately separates blood components using cell-specific light absorption to increase cellular yields. Absorption of 930nm light detects erythrocytes (red cells), absorption of 470nm light detects platelets and leukocytes (white cells), and the 1300nm wavelength corrects for ambient light and detects presence of air bubbles. The resulting fractions, PRP, PPP and erythrocyte concentrate are delivered into separate sterile compartments without manual intervention.


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